'They looked like a normal family': Boy, 15, is arrested with serious injuries after woman dies and girl, 3, and 70-year-old are rushed to hospital as 'violence breaks out inside quiet Melbourne home'

A woman has died and a 15-year-old boy has been arrested after a suspected stabbing rampage inside a home in a quiet suburban Melbourne street. 

The woman, 42, was found with critical stab wounds at a Narre Warren property about 1pm on Monday but later died in hospital, according to 7 News.  

A three-year-old girl and a 70-year-old woman were also taken to hospital in a serious condition.

Police arrested a 15-year-old boy at the scene and took him to hospital under police guard with serious injuries.

A neighbour said from the outside the family seemed to have no issues. 

A woman, 42, has died and a 15-year-old boy has been arrested after a suspected stabbing rampage inside a Melbourne home (forensic officers pictured at scene) 

'They looked like a normal family,' the resident said.

'It is shocking to hear. It must be pretty bad, judging on all the police that are here.' 

The child had also reportedly been stabbed in what is suspected to be a domestic violence-related incident.

The family's two eldest children attend the nearby Narre Warren South P-12 College, The Herald Sun reported.

An elderly woman reportedly lives at the property where she looks after her three grandchildren. 

Witnesses said the family's middle-aged mother was comforting her youngest child on the lawn immediately after the stabbing.

Masked police are seen at the scene after violence broke out at the home. A girl, three, and a 70-year-old woman were also taken to hospital with serious injuries 

A caller on 3AW's Drive with Tom Elliot said she believed 'knives were involved' in the incident. 

Homicide detectives were seen combing the home for evidence on Monday afternoon.

A 150m-long police cordon on the road was set up to stop neighbours from going into their homes. 

Police pictured at the scene on Monday. One of those injured is a three-year-old girl

Homicide detectives on Monday were seen combing the home for evidence, while a 150m-long cordon was set up on Springvalley Way

The police investigation is ongoing on Monday after a 15-year-old boy was arrested at the scene

Authorities are not looking for anyone else over the incident and the police investigation is ongoing.

Residents said half a dozen ambulances were seen rushing to the address on Monday afternoon. 

Parents of students at the nearby school were texted information about road closures in the wake of the stabbing.

Victoria Police pictured at the scene of the stabbing on Monday afternoon. The nearby Narre Warren South P-12 College has been affected by road closures but no children at the school are thought to have been involved in the incident

A Victorian Police detective is pictured at the scene of the stabbing on Monday afternoon. Authorities are not looking for anyone else over the incident

Masked police officers at the scene on Monday. Residents said half a dozen ambulances were seen rushing to the address 

The school is not believed to have gone into lockdown though.

'Investigators are yet to determine the exact circumstances,' a Victoria Police spokesman said.

Anyone with information that could help police with their investigation is urged to contact Crime Stoppers on 1800 333 000.